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CAS 25086-89-9 | PVP/VA Copolymer 64W 73W (USP BP EP grade)
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CAS No.:
25086-89-9 -
Molecular Formula:
(C6H9NO.C4H6O2)x -
Quality Standard:
Food, Pharma, Cosmetic -
Packing:
25kg or 40kg/drum -
Mininmum Order:
25kg -
Price Update:
-
Market:
*If you want to download the TDS and MSDS(SDS) , please click here to view or download online.
CAS 25086-89-9 corresponds to Copovidone, which is a water-soluble linear polymer resin widely used as a pharmaceutical excipient and cosmetic film-forming/styling agent.
Basic Information
-Chinese name: Covidone; Vinyl pyrrolidone vinyl acetate copolymer
-English name: Poly (1-vinylpyrrolidone co vinyl acetate)/Copovidone
-CAS number: 25086-89-9
-Structural unit: N-vinylpyrrolidone (NVP) copolymerized with vinyl acetate (VA), with a VA content of approximately 35.3% -42% in the common specification VA64
-Molecular formula: (C ₆ H ₉ NO · C ₄ H ₆ O ₂) ₙ (repeating unit formula)
-Appearance: White to milky white powder, odorless and tasteless, easy to absorb moisture
-Solubility: soluble in various solvents such as water, ethanol, isopropanol, etc; Insoluble in fatty hydrocarbons, ether, etc
-Density: approximately 1.27 g/mL (25 ° C); glass transition temperature (Tg) is approximately 108 ° C
Main features and applications
1. Pharmaceutical field: As a tablet/granule adhesive (wet, dry granulation or direct compression), film coating material (enhancing flexibility, moisture-proof isolation layer), porogen or solubilizer, in compliance with USP/EP/ChP pharmacopoeia standards.
2. Cosmetics: used as film forming agent and hair styling agent (hair gel, mousse, styling spray) to provide lasting styling and easy cleaning without risk of acne.
3. Other industries: can be used as water-soluble adhesives, ink thickeners, coating dispersion stabilizers, and components of rewetting adhesives.
Safety and Storage
-Safety: Generally considered low toxicity, acute oral LD50 (rat)>630 mg/kg; Avoid inhaling dust and prevent eye contact.
-Stability: Stable, but flammable (especially in powder form), should be kept away from strong oxidants, strong reducing agents, and high-temperature sources of ignition.
-Storage conditions: Sealed and stored in a cool, dry place, moisture-proof.
Specification
| Item | VP/VA | K value | Vinylpyrrolidone | Moisture | Content | PH value (5% aqueous.) | |
| VA73E | 70/30 | 30-38 | <0.2% | <0.5% | 50±2% | - | |
| VA73W | 70/30 | 24-32 | <0.2% | - | 50±2% | 4-7 | |
| VA64E | 60/40 | 30-36 | <0.2% | < 0.5% | 50±2% | - | |
| VA64W | 60/40 | 30-36 | <0.2% | - | 50±2% | 4-7 | |
| VA64(powder) | 60/40 | 26-34 | <0.2% | <5.0% | >95% | 6-8 | |
| VA55E | 50/50 | 28-36 | <0.2% | < 0.5% | 50±2% | - | |
| VA37E | 30/70 | 28-36 | <0.2% | < 0.5% | 50±2% | - | |
Application
Cosmetic:
PVPVA series use as stiffener, its hygroscopic decrease as the ratio of vinyl acetate increase,
it suits for Mousse, hair casehardened liquid, if mix with PVP-K30 can strengthen hardened effect.
Other technological usage
- Use as remoisten binder, bond for paper and coating bond;
- Use as thickener for kinds of paints and protectionability colloids;
- Water-solubility PVP/VA64 series are the usual emulsifier for plant protect agent and protectionability colloid;
- The best bond of preparation effervescence troche in hydro-mixture with absolute ethyl alcoholin
pharmaceutical area. The excellence does not absorpt moisture and has good crushability.
Packing
25kg/fiber drum, 9mt/20″FCL
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