CAS 78491-02-8 corresponds to Diazolinylurea, which is a broad-spectrum cosmetic preservative that works by slow-release formaldehyde. Its trade name is often referred to as Germall II.

Core Basic Information
-Chinese name: Diazoalkylurea (also known as diazoimidazolidinylurea, bis (hydroxymethyl) imidazolidinylurea, Jemma II)
-English name: Diazolinylurea
-Molecular formula: C ₈ H ₁ N ₄ O ₇
-Molecular weight: 278.22
-Appearance: White to grayish white flowing fine powder, with a slight formaldehyde odor, easily soluble in water
-1% aqueous solution pH: 6.0-7.5
-Mechanism of action: Slowly release formaldehyde, inhibit Gram positive/negative bacteria, yeast, and mold
-Main use: antisepsis of cream, lotion, shampoo and other cosmetics and personal care products (typical addition 0.1% – 0.3%, upper limit 0.5% generally)
-Safety reminder: It belongs to the category of formaldehyde releasing preservatives, and some people may develop contact allergies (risk term R43); EU and US allow use, but must comply with concentration restrictions

Precautions
This substance is incompatible with strong oxidants and should be stored in a cool and dry place (recommended to be sealed at 2-8 ℃ or room temperature). Due to its characteristic of releasing formaldehyde, it is necessary to control the concentration of free formaldehyde in the formula and label it as “containing formaldehyde” under label compliance requirements (when the concentration exceeds a specific threshold).

Products :

CAS 78491-02-8 | Diazolidinyl urea (Diazoalkylurea) C4H10N4O
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