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General report of 3-Mercaptopropionic acid (CAS 107-96-0); For Pharmaceutical use


Apr-22-2021

Basic information

CAS NO.: 107-96-0

Chinese aliases: β-mercaptopropionic acid; thiopropionic acid; 3-mercaptopropionic acid; β-thiopropionic acid; β-thiol propionic acid; 3-mercaptopropionic acid (BETA-mercaptopropionic acid)/ 3-thiolactic acid; 3-thiopropionic acid
English name: 3-Mercaptopropionic acid

English alias: 3-MERCAPTO PROPIONATE; 3-MPA; BETA-MERCAPTOPROPIONIC ACID; B-THIOPROPIONIC ACID; β-Mercaptopropionic acid; PROPANOIC ACID, 3-MERCAPTO; PROPONOIC ACID, 3-MERCAPTO; 3-mercapto-propanoicaci; 3-mercaptopropanoicacid; 3-mercapto-Propanoicacid; 3-mercaptopropionic; 3-mercapto-propionicaci; 3-mercpato-propionicaci; 3-Sulfanylpropanoic acid; 3-Thiopropionic acid; 3-thiopropionicacid; acidemercapto-3propionique; beta-mercaptopropanoicacid
EINECS:203-537-0
Molecular formula: C3H6O2S
Molecular weight: 106.14

 
Physical and chemical properties
Appearance: Transparent liquid, strong smell of sulfide, huge odor, and poisonous.
Density 1.218
Melting point 17-19°C
Boiling point 110-111°C (15 mmHg)
Refractive index 1.491-1.493
Flash point 201 °F
Water soluble
Solubility: soluble in water, soluble in most organic solvents such as ethanol, benzene, toluene, ether, chlorinated hydrocarbons 

 

 

Product use
This product is an intermediate of pharmaceutical fennerol and also used as a stabilizer for polyvinyl chloride. It can be used for transparent products like thioglycolic acid, and has very good thermal stability, which is better than other stabilizers. Also used as antioxidants, catalysts and biochemical reagents.

 

 

Production method
It is prepared with acrylonitrile and thiourea as raw materials. First react thiourea with hydrochloric acid at 40°C for 0.5h, add acrylonitrile dropwise, react at 110-113°C for 3h, cool to 40°C, add 4% sodium hydroxide solution to pH 11, dehydrogenate at 30 Neutralize with hydrochloric acid at ℃ to a pH of 1-2. Then add benzene for extraction, recover the benzene, perform vacuum distillation, collect the 125-140°C fractions to obtain the finished product. In addition, 3-mercaptopropionic acid can also be prepared by reacting hydrogen sulfide with pyruvic acid or β-propiolactone.

 
Transportation and storage methods
Store in a cool, ventilated warehouse. Keep away from fire and heat sources. It should be stored separately from oxidants, reducing agents, and alkalis, and avoid mixed storage. Equipped with the appropriate variety and quantity of fire equipment. The storage area should be equipped with leakage emergency treatment equipment and suitable storage materials.

 

Supplier information

Hefei TNJ Chemical is professional factory, manufacturer of 3-Mercaptopropionic acid (CAS 107-96-0) since from 2001 in China. We supply high quality 3-Mercaptopropionic acid (CAS 107-96-0) with purity 99.9%above, which can be used in pharmaceutical grade. If you need to buy 3-Mercaptopropionic acid (CAS 107-96-0), please contact sales@tnjchem.com

 

General report of 3-Mercaptopropionic acid (CAS 107-96-0); For Pharmaceutical use2