CAS No.:
80-08-0Molecular Formula:
C12H12N2O2SQuality Standard:
99.5%min.Packing:
25kg/drum or as per requestMininmum Order:
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CAS 80-08-0 corresponds to Dapsone, chemical name 4,4 ‘- diaminodiphenyl sulfone, which is an organic sulfonyl compound that serves as both an anti leprosy drug and an industrial intermediate.
Basic Information
-Chinese name: Aminobenzenesulfone (alias: DDS, 4,4 ‘- diaminodiphenyl sulfone, 4,4′ – sulfonyldiphenylamine)
-English name: Dapsone/4,4 ‘- Diaminodiphenylsulfone
-Molecular formula: C ₁₂ H ₁₂ N ₂ O ₂ S
-Molecular weight: 248.30
-CAS number: 80-08-0
-EINECS number: 201-248-4
-Appearance: White to slightly yellow crystalline powder, odorless, slightly bitter taste
-Melting point: 175-177 ° C
-Boiling point: approximately 511.7 ° C (atmospheric pressure)
-Density: Approximately 1.33-1.36 g/cm ³
-Solubility: insoluble in water; Dissolve in organic solvents such as ethanol, acetone, chloroform, dilute acid, etc
main purpose
1. Pharmaceutical field: One of the preferred drugs for treating leprosy, which exerts antibacterial effects by inhibiting folate metabolism of Mycobacterium leprae; It is also used as an adjuvant therapy for herpes like dermatitis, certain autoimmune skin diseases (such as systemic lupus erythematosus skin manifestations), stubborn acne, and Pneumocystis pneumonia (with medical advice).
2. In the industrial field, it is used as a curing agent for epoxy resin, gas chromatography stationary liquid, organic synthesis intermediate, and raw material for polymer materials (such as polysulfone amide resin).
Safety and Precautions
-Toxicity characteristics: It is low toxicity but irritating, with the main risks of hemolytic anemia and methemoglobinemia. G6PD deficiency should be used with caution or contraindicated.
-Protection requirements: Dust masks, goggles, anti-seepage gloves, and work clothes are required during operation; Avoid contact with strong oxidants and keep away from heat sources and open flames.
-Storage conditions: Store in a sealed, dark, cool and dry place, separate from oxidants.
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Dapsone (4,4′-Diaminodiphenylsulfone) CAS 80-08-0