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L-Ascorbyl Palmitate AP USP CAS 137-66-6 (Vitamin C Palmitate)

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CAS 137-66-6 corresponds to L-Ascorbyl Palmitate (also known as Vitamin C Palmitate), a fat-soluble antioxidant formed by the esterification of ascorbic acid with palmitic acid, widely used in the food, pharmaceutical, and cosmetic industries.

 

 

 

Core physicochemical properties
Chemical name: 6-Palmitoyl-L-ascorbic acid ((S)-2-[(R)-3,4-Dihydroxy-5-oxo-2,5-dihydro-2-furanyl]-2-hydroxyethyl hexadecanoate)
- Molecular formula/molecular weight: C₂₂H₃₈O₇ / 414.54 g/mol
- Appearance: White to off-white powder with a slight citrus odor
- Melting point: 107~118°C
- Solubility: Soluble in ethanol and methanol; slightly soluble in water and vegetable oil; insoluble in most organic solvents
CAS No.: 137-66-6; EINECS: 205-305-4

 

 

 

Key Functions and Applications
Antioxidant Preservation: As a fat-soluble antioxidant, it significantly delays the oxidative rancidity of animal and vegetable oils, fried foods, instant noodles, and similar products, with effects superior to those of certain synthetic antioxidants (such as BHA/BHT).
2. Nutrient fortification: Provides a stable source of vitamin C, suitable for infant formula, milk powder, and health supplements.
3. Color protection and stability: Assists in maintaining color in meat products and oil-containing foods, preventing metal ion-catalyzed oxidation.
4. Application Fields: Food Additives (GB 16314 Standard), Pharmaceutical Excipients, Cosmetic Stabilizers, and Biomedical Research (e.g., Anti-inflammatory and Apoptosis Research Models).

 

 

 

Safety and Storage
- Acceptable Daily Intake (ADI): The FAO/WHO assessment sets the ADI at 0-1.25 mg/kg body weight; infant food is typically limited to within 200 mg/kg fat.
Storage requirements: Store in a sealed container in a cool, dry place, away from light, high temperatures, and contact with metal ions such as copper and iron to prevent catalytic oxidation.
- Hazard warning: Potentially toxic to aquatic life; waste disposal must comply with regulations.

 

 

 



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