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CAS 57-67-0, Sulphaguanidine, C7H10N4O2S

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The corresponding substance of CAS 57-67-0 is sulfoguanidine, which is a difficult to absorb short acting sulfonamide antibiotic that mainly acts on intestinal infections.

 

 

Core Information
-Chinese name: sulfonamide (also known as sulfamethoxazole, clotrimazole, p-aminobenzenesulfonylguanidine)
-English name: Sulfaguanidine (SG)
-Molecular formula: C ₇ H ₁₀ N ₄ O ₂ S
-Molecular weight: 214.24 g/mol
-Melting point: 190-193 ℃
-Appearance: White to off white crystalline powder, gradually changing color when exposed to light
-Solubility: Slightly soluble in water, soluble in dilute acid and boiling water, insoluble in cold alkaline solution
-EINECS number: 200-345-9

 

 

Main purpose and characteristics
1. Pharmacological effect: It exerts antibacterial effect by inhibiting bacterial folate synthesis and is effective against Gram positive and Gram negative bacteria; Due to minimal oral absorption, it is mainly limited to local antibacterial activity in the intestine.
2. Clinical/application direction: Previously used for preventing infections before bacterial dysentery, enteritis, and intestinal surgery; It is also used as a raw material for synthesizing other sulfonamide drugs, such as sulfamethoxazole.
3. Current situation description: Due to limited efficacy and drug resistance issues, it is currently less commonly used in human medicine clinical practice and is more commonly seen in the field of veterinary medicine or as a research standard/control.

 

 

Safety and Storage
-Stability: Sensitive to light and needs to be stored away from light; incompatible with strong oxidizing agents。
-Storage conditions: It is recommended to seal, avoid light, and store in a cool and dry place (some reagent grades require 2-8 ℃).
-Risk warning: It has a certain degree of irritation, and protective equipment should be worn during operation; Please refer to local regulations and SDS documents for specific hazard classification.

 

 

 

 

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