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Pharmacological action of Furazolidone CAS 67-45-8
This product is a nitrofuran antibacterial drug. It has a certain antibacterial effect on Gram-positive and negative bacteria, including Salmonella, Shigella, Escherichia coli, Klebsiella pneumoniae, Enterobacter, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, and Cholera Vibrio, Campylobacter, Bacteroides, etc. are also active against Trichomonas and Giardia at a certain concentration. Its mechanism of action is to interfere with the bacterial oxidoreductase to block the normal metabolism of bacteria.
Pharmacokinetics OF Furazolidone CAS 67-45-8
This product only absorbs 5% orally. Adults take 1g once, and the blood concentration is 1.7～3.3mg/L, but the drug concentration is kept high in the intestinal tract. Part of the absorbed medicine is excreted with urine.
Indications of Furazolidone CAS 67-45-8
It is mainly used for bacillary dysentery, enteritis and cholera caused by sensitive bacteria. It can also be used for typhoid fever, paratyphoid fever, giardiasis, trichomoniasis, etc. It is used in combination with antacids and other drugs to treat gastritis caused by Helicobacter pylori.
Commodity name: Furazolidone
CAS number: 67-45-8
Molecular formula: C8H7N3O5
Molecular weight: 225.158
Accurate quality: 225.03900
Physical and chemical properties
Appearance and properties: yellow powder or crystalline powder, odorless, initially tasteless and slightly bitter, very slightly soluble in water and ethanol, slightly soluble in chloroform, insoluble in ether, and easily soluble in dimethylformamide and nitromethane.
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Products :CAS No.: 67-45-8 | Furazolidone| C8H7N3O5