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Dibromotriphenylphosphorane CAS 1034-39-5

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CAS 1034-39-5 corresponds to Triphenylphosphine dibromide, which is a highly hygroscopic organic bromination reagent widely used for converting alcohols into alkyl bromides (Appel reaction, etc.).

 

 

Basic Information
-Chinese name: Dibromotriphenylphosphine (also known as dibromotriphenylphosphine)
-English name: Triphenylphosphine dibromide
-Molecular formula: C ₁₈ H ₁₅ Br ₂ P
-Molecular weight: 422.09
-CAS number: 1034-39-5
-EINECS number: 213-855-1
-Appearance: Light yellow to light pink, highly hygroscopic crystalline powder
-Melting point: 235-270 ℃ (decomposition)
-Solubility: soluble in organic solvents such as dichloromethane, acetonitrile, DMF, etc; Extremely sensitive to moisture

 

 

Main uses and reactions
1. Organic brominating agent: efficiently converts alcohols into corresponding alkyl bromides in the Appel reaction.
2. Deoxygenation/activation reagents: can be used for bromination conversion of esters and lactones, or for reaction with amides/ureas to generate intermediates such as isocyanides and carbodiimides.
3. Coupling reaction mediation: Recent studies have revealed its involvement in the construction of C (sp ²) – C (sp ³) bonds under electrochemical conditions.

 

 

Safety and Storage
-Hazard category: Corrosive substances (GHS category 1B skin corrosion, 1 severe eye injury), hazard code R34 (causing burns).
-Storage conditions: It must be sealed and placed in a dry environment at 2-8 ℃, protected by inert gas, and strictly prohibited from coming into contact with moisture, strong alkalis, or strong oxidants.
-Operation protection: It should be carried out in a fume hood, wearing goggles, anti-corrosion gloves, and protective clothing; Transport number UN 3261 (Class 8, PG II).

This reagent is a hazardous chemical, and strict safety regulations must be followed for experimentation and storage.

 

 

 

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