CAS 611-71-2 corresponds to D – (-) – mandelic acid (also known as R-mandelic acid), which is a single right-handed enantiomer of mandelic acid. Its molecular formula is C ₈ H ₈ O3, and its molecular weight is 152.15. It belongs to the class of α – hydroxycarboxylic acid chiral compounds.

Core physical and chemical properties
-Chemical name: (2R) -2-hydroxy-2-phenylacetic acid; English: (R) – (-) – Mandelic acid/D-Mandelic acid
-Appearance: White to off white crystalline or crystalline powder
-Melting point: 131-134 ℃ (the melting point of racemic mandelic acid is about 119 ℃, the two are different)
-Specific optical rotation: [α] D ² ⁰ ≈ -150 ° to -157.5 ° (aqueous solution, c=2-2.5)
-Solubility: Easily soluble in water, ethanol, ether, acetic acid DMSO； Slightly soluble in chloroform
-Acidity coefficient (pKa): approximately 3.37 (25 ℃)
-Stability: Sensitive to light, prone to discoloration and decomposition upon prolonged exposure to light; Store in a dark, sealed, and dry place

Source and purpose
-Natural source: mainly extracted from plants such as bitter almonds
-Main applications:
1. Chiral separating agent: widely used for optical separation of racemates (especially alpha amino acids)
2. Pharmaceutical intermediates: synthesis of cephalosporin antibiotics, cyclohexanel esters, antispasmodics, etc
3. Research reagents: Asymmetric synthesis, chiral catalysis research, and biological activity testing (with antibacterial and antioxidant potential)
4. Fine Chemicals: Preparation of chiral liquid crystal materials, pesticide intermediates, etc

Safety and Storage
-Danger: Irritable to eyes and skin (risk code R36/37/38), avoid inhaling dust
-Storage conditions: Store in a cool (<30 ℃), dry, and sealed place away from light; Long term storage recommendation -20 ℃
-Note: CAS 611-71-2 specifically refers to the D – (-) – configuration; The CAS for racemic mandelic acid is 611-72-3, and the CAS for L – (-) – mandelic acid (S-configuration) is 17199-29-0. Do not confuse them.

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(R)-(-)-Mandelic acid CAS 611-71-2
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