CAS 4083-64-1 is a highly reactive organic synthetic intermediate and dehydrating agent that reacts violently with water and has tear inducing properties.

Basic Information
-Chinese name: p-toluenesulfonyl isocyanate (alias: p-toluenesulfonyl isocyanate)
-English name: p-Toluenesulfonyl isocyanate/Tosyl isocyanate
-Molecular formula: C ₈ H ₇ NO ∝ S
-Molecular weight: 197.21
-EINECS number: 223-810-8
-Appearance: Colorless and transparent liquid, low viscosity, with a pungent odor (tear gas)

Key physical and chemical properties
-Density: Approximately 1.27-1.30 g/cm ³
-Boiling point: 288.8 ° C (760 mmHg) or 144 ° C (10 mmHg)
-Flash point: 128.5-145 ° C
-Water solubility: reacts violently with water (cannot be added with water)
-Refractive index: 1.533-1.535
-Storage conditions: Dry, sealed, away from light, in a cool and shady place (recommended dry environment at 2-8 ° C or room temperature)

main purpose
-Intermediate for the synthesis of pharmaceuticals and pesticides (such as the preparation of drugs such as doxazosin)
-Dehydrating agents in organic synthesis
-Used as a solvent, filler auxiliary, or asphalt tar dehydration treatment in the paint industry

Safety and Hazards
-Hazardous characteristics: Reacts violently when in contact with water (R14); Inhalation sensitization (R42); Irritation to eyes, respiratory tract, and skin (R36/37/38)
-Protection requirements: Avoid contact with moisture; Protective goggles, gloves, and ventilation facilities are required during operation; In case of eye contact, rinse immediately and seek medical attention
-Transport number: UN 2206 (hazardous substance)
-Logo: Xn (Harmful)

This substance is a hazardous chemical and must be stored and transported strictly in accordance with regulations. It is strictly prohibited to come into contact with water.

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Tosyl isocyanate CAS 4083-64-1
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